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Amuvatinib hydrochloride

Product Specifications

CAS Number

1055986-67-8

Target

Others, c-Kit, PDGFR, DNA/RNA Synthesis, c-Met/HGFR, FLT, c-RET

Related Pathways

DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Angiogenesis, Apoptosis, Others, Tyrosine Kinase/Adaptors

Bioactivity

Amuvatinib hydrochloride (MP470 hydrochloride) is an orally administered multi-targeted tyrosine kinase inhibitor effective against mutant forms of c-Kit, PDGFRα, Flt3, c-Met, and c-Ret, and it suppresses DNA repair by inhibiting the RAD51 protein, contributing to its antineoplastic activity[1][2][3][4].

Smiles

Cl.S=C(NCc1ccc2OCOc2c1)N1CCN(CC1)c1ncnc2c3ccccc3oc12

Molecular Formula

C23H22ClN5O3S

Molecular Weight

483.97

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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