Amuvatinib hydrochloride
Product Specifications
CAS Number
1055986-67-8
Target
Others, c-Kit, PDGFR, DNA/RNA Synthesis, c-Met/HGFR, FLT, c-RET
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Angiogenesis, Apoptosis, Others, Tyrosine Kinase/Adaptors
Bioactivity
Amuvatinib hydrochloride (MP470 hydrochloride) is an orally administered multi-targeted tyrosine kinase inhibitor effective against mutant forms of c-Kit, PDGFRα, Flt3, c-Met, and c-Ret, and it suppresses DNA repair by inhibiting the RAD51 protein, contributing to its antineoplastic activity[1][2][3][4].
Smiles
Cl.S=C(NCc1ccc2OCOc2c1)N1CCN(CC1)c1ncnc2c3ccccc3oc12
Molecular Formula
C23H22ClN5O3S
Molecular Weight
483.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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