Amuvatinib hydrochloride
Product Specifications
CAS Number
1055986-67-8
Target
Others|||c-Kit|||PDGFR|||DNA/RNA Synthesis|||c-Met/HGFR|||FLT|||c-RET
Related Pathways
DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Angiogenesis|||Apoptosis|||Others|||Tyrosine Kinase/Adaptors
Bioactivity
Amuvatinib hydrochloride (MP470 hydrochloride) is an orally administered multi-targeted tyrosine kinase inhibitor effective against mutant forms of c-Kit, PDGFR?, Flt3, c-Met, and c-Ret, and it suppresses DNA repair by inhibiting the RAD51 protein, contributing to its antineoplastic activity[1][2][3][4].
Smiles
Cl.S=C(NCc1ccc2OCOc2c1)N1CCN(CC1)c1ncnc2c3ccccc3oc12
Molecular Formula
C23H22ClN5O3S
Molecular Weight
483.97
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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