AM-4668
Product Specifications
CAS Number
1011531-27-3
Target
GPCR
Related Pathways
GPCR/G Protein, Endocrinology/Hormones
Purity
0.9992
Bioactivity
AM-4668, a GPR40 (FFA1) agonist with oral availability, was optimized to reduce central nervous system (CNS) permeability, with a mouse brain/plasma ratio of only 0.02, and significantly reduced blood glucose levels in human GPR40 knock-in mice.
Smiles
C(OC1=CC=C([C@H](CC(O)=O)C=2C=CON2)C=C1)C=3SC(=NC3C)C4=CC=C(C(F)(F)F)C=C4
Molecular Formula
C24H19F3N2O4S
Molecular Weight
488.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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