Alpelisib hydrochloride
Product Specifications
CAS Number
1584128-91-5
Target
PI3K
Related Pathways
PI3K/Akt/mTOR signaling
Purity
0.9764
Bioactivity
Alpelisib hydrochloride (BYL-719 hydrochloride) is a potent PI3K? inhibitor (IC?? = 5 nM) with selectivity and oral bioavailability, exhibiting activity against PI3K?/?/? that is dozens of times weaker than against PI3K? (IC?? = 250/290/1200 nM) . Alpelisib exhibits targeting activity against PIK3CA-mutated tumors and may be utilized in cancer research.
Smiles
CC1=C(C=2C=C(C(C(F)(F)F)(C)C)N=CC2)SC(NC(=O)N3[C@H](C(N)=O)CCC3)=N1.Cl
Molecular Formula
C19H23ClF3N5O2S
Molecular Weight
477.93
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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