AGI-24512
Product Specifications
CAS Number
2201066-53-5
Target
Methionine Adenosyltransferase (MAT), DNA
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair
Purity
0.9855
Bioactivity
AGI-24512 is a potent inhibitor of methionine adenylyltransferase 2α (MAT2A) (IC50: 8 nM) .AGI-24512 shows antiproliferative activity in MTAP-deficient cancer cells.AGI-24512 inhibits MAT2A, which causes DNA damage in MTAP, and is often used in conjunction with anticancer compounds in cancer research.
Smiles
Cc1[nH]c2c(N3CCCCC3)c(nn2c(=O)c1-c1ccc(O)cc1)-c1ccccc1
Molecular Formula
C24H24N4O2
Molecular Weight
400.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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