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AA147

Product Specifications

CAS Number

393121-74-9

Target

Others, Reactive Oxygen Species, ROS

Related Pathways

Metabolism, Immunology/Inflammation, NF-κB, Others

Purity

0.9979

Bioactivity

AA147 (ATF6-activator-147) is a small molecule endoplasmic reticulum (ER) proteostasis regulator. The selectively activates ATF6 arm of the unfolded protein response (UPR) .It acts as a prodrug that preferentially triggers ATF6 signaling through a mechanism involving localized metabolic activation and selective covalent modification of ER resident proteins that regulate ATF6 activity.

Smiles

Cc1ccc(O)c(NC(=O)CCc2ccccc2)c1

Molecular Formula

C16H17NO2

Molecular Weight

255.31

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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