AA147
Product Specifications
CAS Number
393121-74-9
Target
Others|||Reactive Oxygen Species|||ROS
Related Pathways
Metabolism|||Immunology/Inflammation|||NF-?B|||Others
Purity
0.9979
Bioactivity
AA147 (ATF6-activator-147) is a small molecule endoplasmic reticulum (ER) proteostasis regulator. The selectively activates ATF6 arm of the unfolded protein response (UPR) .It acts as a prodrug that preferentially triggers ATF6 signaling through a mechanism involving localized metabolic activation and selective covalent modification of ER resident proteins that regulate ATF6 activity.
Smiles
Cc1ccc(O)c(NC(=O)CCc2ccccc2)c1
Molecular Formula
C16H17NO2
Molecular Weight
255.31
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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