A-770041
Product Specifications
CAS Number
869748-10-7
Target
Src
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Purity
0.9986
Bioactivity
A-770041 is an orally active and selective Lck inhibitor that inhibits concanavalin A-stimulated IL-2 production in whole blood and prevents cardiac allograft rejection. A-770041 reduces pulmonary fibrosis by inhibiting TGF-β production in regulatory T cells.
Smiles
NC1=C2C(=NN(C2=NC=N1)[C@H]3CC[C@@H](CC3)N4CCN(C(C)=O)CC4)C5=CC(OC)=C(NC(=O)C6=CC=7C(N6C)=CC=CC7)C=C5
Molecular Formula
C34H39N9O3
Molecular Weight
621.73
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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