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A-485

Product Specifications

CAS Number

1889279-16-6

Target

Epigenetic Reader Domain, Histone Acetyltransferase

Related Pathways

Chromatin/Epigenetic

Purity

>99.99%

Bioactivity

A-485 is a potent and selective catalytic p300/CBP inhibitor with IC50 values of 9.8 nM for p300 and 2.6 nM for CBP.

Smiles

CNC(=O)Nc1ccc2c(CC[C@@]22OC(=O)N(CC(=O)N(Cc3ccc(F)cc3)[C@@H](C)C(F)(F)F)C2=O)c1

Molecular Formula

C25H24F4N4O5

Molecular Weight

536.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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