A-443654

Product Specifications

CAS Number

552325-16-3

Target

PKA|||PKC|||Src|||Chk|||VEGFR|||Akt|||FLT|||Casein Kinase|||ERK|||MAPK|||GSK-3|||S6 Kinase|||CDK

Related Pathways

Cell Cycle/Checkpoint|||Stem Cells|||MAPK|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling|||Angiogenesis|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors|||Metabolism

Purity

0.9951

Bioactivity

A-443654, a pan-Akt inhibitor, exhibits equal potency against Akt1, Akt2, and Akt3 within cells (Ki=160 pM) .

Smiles

C([C@@H](COC=1C=C(C=NC1)C=2C=C3C(=CC2)NN=C3C)N)C=4C=5C(NC4)=CC=CC5

Molecular Formula

C24H23N5O

Molecular Weight

397.47

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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