A-443654
Product Specifications
CAS Number
552325-16-3
Target
PKA|||PKC|||Src|||Chk|||VEGFR|||Akt|||FLT|||Casein Kinase|||ERK|||MAPK|||GSK-3|||S6 Kinase|||CDK
Related Pathways
Cell Cycle/Checkpoint|||Stem Cells|||MAPK|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling|||Angiogenesis|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors|||Metabolism
Purity
0.9951
Bioactivity
A-443654, a pan-Akt inhibitor, exhibits equal potency against Akt1, Akt2, and Akt3 within cells (Ki=160 pM) .
Smiles
C([C@@H](COC=1C=C(C=NC1)C=2C=C3C(=CC2)NN=C3C)N)C=4C=5C(NC4)=CC=CC5
Molecular Formula
C24H23N5O
Molecular Weight
397.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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