A-3 hydrochloride
Product Specifications
CAS Number
78957-85-4
Target
PKC, PKA, Casein Kinase, CaMK
Related Pathways
Neuroscience, Stem Cells, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Cytoskeletal Signaling, Metabolism
Purity
0.9979
Bioactivity
A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It inhibits PKC and casein kinase I with Ki values of 47 μM and 80 μM, respectively[1], and also inhibits PKA (Ki=4.3 μM), casein kinase II (Ki=5.1 μM), and myosin light chain kinase (MLCK) (Ki=7.4 μM) .
Smiles
Cl.NCCNS(=O)(=O)c1cccc2c(Cl)cccc12
Molecular Formula
C12H14Cl2N2O2S
Molecular Weight
321.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
243008-Biotin 100 µL
ABTB1 (Ankyrin Repeat and BTB (POZ) Domain Containing 1, BPOZ, Btb3, EF1ABP, MGC20585, PP2259) (Biotin)
Sign In for Pricing
View Details