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A-3 hydrochloride

Product Specifications

CAS Number

78957-85-4

Target

PKC, PKA, Casein Kinase, CaMK

Related Pathways

Neuroscience, Stem Cells, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Cytoskeletal Signaling, Metabolism

Purity

0.9979

Bioactivity

A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It inhibits PKC and casein kinase I with Ki values of 47 μM and 80 μM, respectively[1], and also inhibits PKA (Ki=4.3 μM), casein kinase II (Ki=5.1 μM), and myosin light chain kinase (MLCK) (Ki=7.4 μM) .

Smiles

Cl.NCCNS(=O)(=O)c1cccc2c(Cl)cccc12

Molecular Formula

C12H14Cl2N2O2S

Molecular Weight

321.22

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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