A-3 hydrochloride
Product Specifications
CAS Number
78957-85-4
Target
PKC|||PKA|||Casein Kinase|||CaMK
Related Pathways
Neuroscience|||Stem Cells|||Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||Metabolism
Purity
0.9979
Bioactivity
A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It inhibits PKC and casein kinase I with Ki values of 47 ?M and 80 ?M, respectively[1], and also inhibits PKA (Ki=4.3 ?M), casein kinase II (Ki=5.1 ?M), and myosin light chain kinase (MLCK) (Ki=7.4 ?M) .
Smiles
Cl.NCCNS(=O)(=O)c1cccc2c(Cl)cccc12
Molecular Formula
C12H14Cl2N2O2S
Molecular Weight
321.22
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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