5Z-7-Oxozeaenol
Product Specifications
CAS Number
253863-19-3
Target
Src, PDGFR, MAPK, MEK, VEGFR, FLT, Antibiotic
Related Pathways
MAPK, Angiogenesis, Microbiology/Virology, Tyrosine Kinase/Adaptors
Purity
0.99
Bioactivity
5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF) -β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is also an inhibitor of VEGF-R2 with IC50 of 52 nM.
Smiles
COc1cc(O)c2c(c1)\C=C\C[C@H](O)[C@H](O)C(=O)\C=C/C[C@H](C)OC2=O
Molecular Formula
C19H22O7
Molecular Weight
362.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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