Tubulysin H
Product Specifications
CAS Number
799822-09-6
Target
Microtubule Associated, ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related, Cytoskeletal Signaling
Bioactivity
Tubulysin H is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide. Tubulysin H is a cytotoxic activity tubulysin that inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis.
Smiles
[C@H](C[C@@H](N(C([C@@H](NC(=O)[C@@H]1N(C)CCCC1)[C@H](CC)C)=O)COC(C)=O)C(C)C)(OC(C)=O)C2=NC(C(N[C@@H](CC3=CC=CC=C3)C[C@@H](C(O)=O)C)=O)=CS2
Molecular Formula
C40H59N5O9S
Molecular Weight
785.99
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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