TL13-12
Product Specifications
CAS Number
2229037-04-9
Target
PROTACs|||ALK
Related Pathways
PROTAC|||Tyrosine Kinase/Adaptors|||Angiogenesis
Bioactivity
TL13-12 is a selective degrader of ALK-PROTAC and inhibits ALK activity (IC50: 0.69 nM) .
Smiles
COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1)N1CCN(CCOCCOCCNC(=O)CNc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)CC1
Molecular Formula
C45H53ClN10O10S
Molecular Weight
961.49
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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