THS-044
Product Specifications
CAS Number
62054-67-5
Target
HIF/HIF Prolyl-Hydroxylase, HIF
Related Pathways
Metabolism, Angiogenesis, Chromatin/Epigenetic
Purity
>99.99%
Bioactivity
THS-044 (N-[2-Nitro-4- (Trifluoromethyl) phenyl]morpholin-4-Amine) binding stabilizes the HIF2α PAS-B folded state with a kd of 2 μM and regulates HIF2 activity in endogenous and clinical settings.
Smiles
[O-][N+](=O)c1cc(ccc1NN1CCOCC1)C(F)(F)F
Molecular Formula
C11H12F3N3O3
Molecular Weight
291.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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