PROTAC PARP1 degrader
Product Specifications
CAS Number
2369022-68-2
Target
Others, PROTACs, PARP
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic, PROTAC, Others
Bioactivity
PROTAC PARP1 degrader is a degrader of PARP1 based on the PROTAC technology. PROTAC PARP1 degrader at 10 μM at 24 h inhibits MDA-MB-231 cell line (IC50 of 6.12 μM) .
Smiles
C(=O)(N1[C@]([C@](N=C1C2=C(OC(C)C)C=C(OC)C=C2)(C3=CC=C(Cl)C=C3)[H])(C4=CC=C(Cl)C=C4)[H])N5CC(=O)N(CC(NCCOCCOCCOCCOCCN6C=C(N=N6)C7=CC=C(C=C7)N8N=C9C(=C8)C=CC=C9C(N)=O)=O)CC5
Molecular Formula
C58H63Cl2N11O10
Molecular Weight
1145.1
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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