PROTAC FAK degrader 1

2301916-69-6

Akt, PROTACs, FAK

Angiogenesis, PROTAC, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors

PROTAC FAK degrader 1 is a selective and potent degrader of focal adhesion kinase (Fak) with an IC50 of 6.5 nM.

CN(c1cccc(CNc2nc(Nc3ccc(OCCOCCC(=O)N[C@H](C(=O)N4C[C@H](O)C[C@H]4C(=O)NCc4ccc(cc4)-c4scnc4C)C(C)(C)C)cc3)ncc2C(F)(F)F)c1)S(C)(=O)=O

C47H56F3N9O8S2

996.13

Ice Packs

-20°C