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PROTAC FAK degrader 1

Product Specifications

CAS Number

2301916-69-6

Target

Akt, PROTACs, FAK

Related Pathways

Angiogenesis, PROTAC, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors

Bioactivity

PROTAC FAK degrader 1 is a selective and potent degrader of focal adhesion kinase (Fak) with an IC50 of 6.5 nM.

Smiles

CN(c1cccc(CNc2nc(Nc3ccc(OCCOCCC(=O)N[C@H](C(=O)N4C[C@H](O)C[C@H]4C(=O)NCc4ccc(cc4)-c4scnc4C)C(C)(C)C)cc3)ncc2C(F)(F)F)c1)S(C)(=O)=O

Molecular Formula

C47H56F3N9O8S2

Molecular Weight

996.13

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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