PROTAC FAK degrader 1
Product Specifications
CAS Number
2301916-69-6
Target
Akt, PROTACs, FAK
Related Pathways
Angiogenesis, PROTAC, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors
Bioactivity
PROTAC FAK degrader 1 is a selective and potent degrader of focal adhesion kinase (Fak) with an IC50 of 6.5 nM.
Smiles
CN(c1cccc(CNc2nc(Nc3ccc(OCCOCCC(=O)N[C@H](C(=O)N4C[C@H](O)C[C@H]4C(=O)NCc4ccc(cc4)-c4scnc4C)C(C)(C)C)cc3)ncc2C(F)(F)F)c1)S(C)(=O)=O
Molecular Formula
C47H56F3N9O8S2
Molecular Weight
996.13
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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