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MS432

Product Specifications

Target

PROTACs, MEK

Related Pathways

MAPK, PROTAC

Bioactivity

MS432 is a highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2.

Smiles

O=C(N[C@@H](C)C1=CC=C(C=C1)C2=C(N=CS2)C)[C@H]3C[C@@H](O)CN3C([C@@H](NC(CCCCCCCCCCNCCCONC(C4=CC=C(C(F)=C4NC5=CC=C(C=C5F)I)F)=O)=O)C(C)(C)C)=O

Molecular Formula

C50H65F3IN7O6S

Molecular Weight

1076.06

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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