Homocarbonyltopsentin
Product Specifications
CAS Number
172286-77-0
Target
Others|||DNA/RNA Synthesis
Related Pathways
Others|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint
Bioactivity
Homocarbonyltopsentin is a small-molecule TSL2-binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing (EC50: 16 ?M) .
Smiles
Oc1ccc2c(c[nH]c2c1)C(=O)c1ncc([nH]1)C(=O)c1c[nH]c2ccccc12
Molecular Formula
C21H14N4O3
Molecular Weight
370.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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