GLPG2451
Product Specifications
CAS Number
2055015-61-5
Target
CFTR
Related Pathways
Membrane transporter/Ion channel
Purity
0.9913
Bioactivity
GLPG2451 is an effective CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) enhancer that potentiates cold-rescued F508del CFTR (EC50=11.1 nM), suitable for cystic fibrosis research.
Smiles
S(=O)(=O)(C=1C=C(N)C(C(NC[C@H](C)O)=O)=NC1)C2=CC=C(OC(F)(F)F)C=C2
Molecular Formula
C16H16F3N3O5S
Molecular Weight
419.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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