GLPG2451

Product Specifications

CAS Number

2055015-61-5

Target

CFTR

Related Pathways

Membrane transporter/Ion channel

Purity

0.9913

Bioactivity

GLPG2451 is an effective CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) enhancer that potentiates cold-rescued F508del CFTR (EC50=11.1 nM), suitable for cystic fibrosis research.

Smiles

S(=O)(=O)(C=1C=C(N)C(C(NC[C@H](C)O)=O)=NC1)C2=CC=C(OC(F)(F)F)C=C2

Molecular Formula

C16H16F3N3O5S

Molecular Weight

419.38

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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