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GLPG-3221

Product Specifications

CAS Number

2222264-64-2

Target

Others, CFTR

Related Pathways

Others, Membrane transporter/Ion channel

Bioactivity

GLPG-3221 can be uesd for the treatment of cystic fibrosis.GLPG-3221 is a potent, orally active corrector of CFTR (cystic fibrosis transmembrane conductance regulator), with an EC50 of 105 nM.

Smiles

C(=O)(N1[C@H]([C@@H](OCC2=C(OC)N=CC(C(F)(F)F)=C2)[C@H]([C@](C)(C)C)[C@H]1C(O)=O)C3=C(C)C=CC=C3)[C@@H]4CCCCO4

Molecular Formula

C30H37F3N2O6

Molecular Weight

578.62

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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