Enniatin B1
Product Specifications
CAS Number
19914-20-6
Target
ERK, NF-κB, Acyltransferase
Related Pathways
NF-κB, Metabolism, MAPK
Bioactivity
Enniatin B1, a Fusarium mycotoxin, crosses the blood-brain barrier, decreases the activation of ERK (p44/p42), and inhibits moderately TNF-α-induced NF-κB activation. Furthermore, it inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity, exhibiting an IC50 of 73 μM in rat liver microsome enzyme assays.
Smiles
[H][C@@]1([C@@H](C)CC)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C(=O)[C@H](OC1=O)C(C)C)C(C)C)C(C)C
Molecular Formula
C34H59N3O9
Molecular Weight
653.858
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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