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AZ7550

Product Specifications

CAS Number

1421373-99-0

Target

MNK, FLT, MLK, PYK2, FAK, EGFR, BTK, ALK, Drug Metabolite, IGF-1R, Tyrosine Kinases, ACK1

Related Pathways

Metabolism, Cytoskeletal Signaling, MAPK, Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

Purity

0.9975

Bioactivity

AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM) .

Smiles

CN1C=C(C=2C1=CC=CC2)C3=NC(NC4=C(OC)C=C(N(CCNC)C)C(NC(C=C)=O)=C4)=NC=C3

Molecular Formula

C27H31N7O2

Molecular Weight

485.58

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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