AP5
Product Specifications
CAS Number
1623194-37-5
Target
Others|||GPCR
Related Pathways
GPCR/G Protein|||Others|||Endocrinology/Hormones
Bioactivity
AP5 is a potent and selective agonist for the GPR40 receptor with positive allosteric modulation of endogenous ligands (AgoPAM) . AP5 demonstrates a rat hIP1 EC50 of 0.49 nM against the GPR40 receptor.
Smiles
[C@@H]([C@@H](C(O)=O)C)(C=1C=C2C(=CC1)CC[C@H](O2)C3=C(F)C=C(C=C3)C=4C=C(OC)N=CC4)[C@H]5CC5
Molecular Formula
C28H28FNO4
Molecular Weight
461.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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