AP5

Product Specifications

CAS Number

1623194-37-5

Target

Others, GPCR

Related Pathways

GPCR/G Protein, Others, Endocrinology/Hormones

Bioactivity

AP5 is a potent and selective agonist for the GPR40 receptor with positive allosteric modulation of endogenous ligands (AgoPAM) . AP5 demonstrates a rat hIP1 EC50 of 0.49 nM against the GPR40 receptor.

Smiles

[C@@H]([C@@H](C(O)=O)C)(C=1C=C2C(=CC1)CC[C@H](O2)C3=C(F)C=C(C=C3)C=4C=C(OC)N=CC4)[C@H]5CC5

Molecular Formula

C28H28FNO4

Molecular Weight

461.52

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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