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FLT3-IN-16

FLT3-IN-16 is a potent FLT3 inhibitor with an IC50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia[1].

Product Specifications

CAS Number

[298207-49-5]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

FLT3

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/flt3-in-16.html

Concentration

10mM

Purity

98.98

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

O=C(C1=C(NC(C2=CC=CN=C2)=O)SC3=C1CCCC3)N

Molecular Formula

C15H15N3O2S

Molecular Weight

301.36

Precautions

H315, H319

References & Citations

[1]Patch RJ, et, al. Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3. Bioorg Med Chem Lett. 2006 Jun 15;16 (12) :3282-6.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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