FLT3-IN-16
FLT3-IN-16 is a potent FLT3 inhibitor with an IC50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia[1].
Product Specifications
CAS Number
[298207-49-5]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
FLT3
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/flt3-in-16.html
Concentration
10mM
Purity
98.98
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=C(C1=C(NC(C2=CC=CN=C2)=O)SC3=C1CCCC3)N
Molecular Formula
C15H15N3O2S
Molecular Weight
301.36
Precautions
H315, H319
References & Citations
[1]Patch RJ, et, al. Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3. Bioorg Med Chem Lett. 2006 Jun 15;16 (12) :3282-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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