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(R) -BAY1238097

Product Specifications

CAS Number

1564269-85-7

Target

Epigenetic Reader Domain

Related Pathways

Chromatin/Epigenetic

Purity

0.9877

Bioactivity

(R) -BAY1238097 represents the R-isomer of BAY1238097, which exhibits relatively lower activity compared to its counterpart. BAY1238097 is a highly potent and selective inhibitor targeting the binding of BET proteins to histones, demonstrating significant anti-proliferative effects in various acute myeloid leukemia (AML) and multiple myeloma (MM) models. The high activity is achieved through the down-regulation of c-Myc levels and the subsequent modulation of its downstream transcriptome.

Smiles

O(C)C=1C=C2C(=NN(C(NC)=O)[C@H](C)CC2=CC1OC)C3=CC=C(C=C3)N4CCN(C)CC4

Molecular Formula

C25H33N5O3

Molecular Weight

451.56

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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