(R) -BAY1238097
Product Specifications
CAS Number
1564269-85-7
Target
Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Purity
0.9877
Bioactivity
(R) -BAY1238097 represents the R-isomer of BAY1238097, which exhibits relatively lower activity compared to its counterpart. BAY1238097 is a highly potent and selective inhibitor targeting the binding of BET proteins to histones, demonstrating significant anti-proliferative effects in various acute myeloid leukemia (AML) and multiple myeloma (MM) models. The high activity is achieved through the down-regulation of c-Myc levels and the subsequent modulation of its downstream transcriptome.
Smiles
O(C)C=1C=C2C(=NN(C(NC)=O)[C@H](C)CC2=CC1OC)C3=CC=C(C=C3)N4CCN(C)CC4
Molecular Formula
C25H33N5O3
Molecular Weight
451.56
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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