TR antagonist 1
Product Specifications
CAS Number
500794-88-7
Target
Thyroid hormone receptor (THR)
Related Pathways
Endocrinology/Hormones
Purity
0.9957
Bioactivity
TR antagonist 1 is a highly potent thyroid hormone receptor (TR) antagonist (IC50 of 36 and 22 nM for TRα and TRβ, respectively) that can be used to study diseases caused by endocrine abnormalities.
Smiles
CC(C)c1cc(Oc2c(Br)cc(CCC(O)=O)cc2Br)cc(\C=C\c2ccncc2)c1O
Molecular Formula
C25H23Br2NO4
Molecular Weight
561.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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