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TR antagonist 1

Product Specifications

CAS Number

500794-88-7

Target

Thyroid hormone receptor (THR)

Related Pathways

Endocrinology/Hormones

Purity

0.9957

Bioactivity

TR antagonist 1 is a highly potent thyroid hormone receptor (TR) antagonist (IC50 of 36 and 22 nM for TR? and TR?, respectively) that can be used to study diseases caused by endocrine abnormalities.

Smiles

CC(C)c1cc(Oc2c(Br)cc(CCC(O)=O)cc2Br)cc(\C=C\c2ccncc2)c1O

Molecular Formula

C25H23Br2NO4

Molecular Weight

561.26

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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