(1S,3R,5R) -PIM447 dihydrochloride
Product Specifications
Target
Pim, CDK
Related Pathways
Chromatin/Epigenetic, Cell Cycle/Checkpoint, JAK/STAT signaling
Bioactivity
(1S,3R,5R) -PIM447 (dihydrochloride) is an inhibitor of PIM with IC50 values of 0.095 μM for Pim1, 0.522 μM for Pim2, and 0.369 μM for Pim3.
Smiles
O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=C([C@@H]4C[C@H](N)C[C@H](C)C4)C=CN=C3.Cl.Cl
Molecular Formula
C24H25Cl2F3N4O
Molecular Weight
513.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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