ZX-29
Product Specifications
CAS Number
2254805-62-2
Target
ALK, Autophagy, Apoptosis
Related Pathways
Autophagy, Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis
Purity
0.9951
Bioactivity
ZX-29 is a potent and selective inhibitor of ALK with IC50 values of 2.1 nM, 1.3 nM, and 3.9 nM for ALK, ALK [L1196M], and ALK [G1202R] mutations, respectively. It also induces protective autophagy and exhibits antitumor effects.
Smiles
COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCN(C)CC1
Molecular Formula
C23H28ClN7O3S
Molecular Weight
518.03
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K2583902 1.0 µg DNA
UGT1A7 sgRNA CRISPR Lentivector (Human) (Target 1)
Sign In for Pricing
View Details 
FAB173D 0.1 mL
Mouse Monoclonal CXCR4 Antibody (44717) [DyLight 350]
Sign In for Pricing
View Details