ZX-29
Product Specifications
CAS Number
2254805-62-2
Target
ALK, Autophagy, Apoptosis
Related Pathways
Autophagy, Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis
Purity
0.9951
Bioactivity
ZX-29 is a potent and selective inhibitor of ALK with IC50 values of 2.1 nM, 1.3 nM, and 3.9 nM for ALK, ALK [L1196M], and ALK [G1202R] mutations, respectively. It also induces protective autophagy and exhibits antitumor effects.
Smiles
COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCN(C)CC1
Molecular Formula
C23H28ClN7O3S
Molecular Weight
518.03
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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