ZX-29

Product Specifications

CAS Number

2254805-62-2

Target

ALK|||Autophagy|||Apoptosis

Related Pathways

Autophagy|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Apoptosis

Purity

0.9951

Bioactivity

ZX-29 is a potent and selective inhibitor of ALK with IC50 values of 2.1 nM, 1.3 nM, and 3.9 nM for ALK, ALK [L1196M], and ALK [G1202R] mutations, respectively. It also induces protective autophagy and exhibits antitumor effects.

Smiles

COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCN(C)CC1

Molecular Formula

C23H28ClN7O3S

Molecular Weight

518.03

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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