ZK824190

Product Specifications

CAS Number

2254001-81-3

Target

PAI-1|||Serine Protease

Related Pathways

Proteases/Proteasome|||Metabolism

Purity

0.9884

Bioactivity

ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA), with IC50 values of 237 nM for uPA, 1600 nM for tPA, and 1850 nM for Plasmin.

Smiles

O(C=1C=C(C=CC1)C2=CC(CN)=CC=C2)C=3N=C(O[C@@H](C(O)=O)CC)C(F)=CC3F

Molecular Formula

C22H20F2N2O4

Molecular Weight

414.4

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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