Zamicastat
Product Specifications
CAS Number
1080028-80-3
Target
BCRP, P-gp, Hydroxylase
Related Pathways
Membrane transporter/Ion channel, Neuroscience, Metabolism
Purity
0.9958
Bioactivity
Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH) and a concentration-dependent dual inhibitor of P-gp and BCRP, with IC50 values of 73.8 μM and 17.0 μM, respectively.
Smiles
Fc1cc(F)c2OC[C@@H](Cc2c1)n1c(CCNCc2ccccc2)c[nH]c1=S
Molecular Formula
C21H21F2N3OS
Molecular Weight
401.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS7235967-01 48 Well
Canine Ankyrin repeat and SOCS box protein 16 (ASB16) ELISA Kit
Sign In for Pricing
View Details MBS7235967-02 96 Well
Canine Ankyrin repeat and SOCS box protein 16 (ASB16) ELISA Kit
Sign In for Pricing
View Details MBS7235967-03 5x 96 Well
Canine Ankyrin repeat and SOCS box protein 16 (ASB16) ELISA Kit
Sign In for Pricing
View Details MBS7235967-04 10x 96 Well
Canine Ankyrin repeat and SOCS box protein 16 (ASB16) ELISA Kit
Sign In for Pricing
View Details GTR15191631 1 Vial
Lentiviral mouse Rfc5 shRNA (UAS) - Lentiviral mouse Rfc5 shRNA (UAS, iRFP) (100)
Sign In for Pricing
View Details 