Zamicastat
Product Specifications
CAS Number
1080028-80-3
Target
BCRP, P-gp, Hydroxylase
Related Pathways
Membrane transporter/Ion channel, Neuroscience, Metabolism
Purity
0.9958
Bioactivity
Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH) and a concentration-dependent dual inhibitor of P-gp and BCRP, with IC50 values of 73.8 μM and 17.0 μM, respectively.
Smiles
Fc1cc(F)c2OC[C@@H](Cc2c1)n1c(CCNCc2ccccc2)c[nH]c1=S
Molecular Formula
C21H21F2N3OS
Molecular Weight
401.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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