VTP50469 fumarate
Product Specifications
CAS Number
2169919-29-1
Target
Others, Apoptosis, Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic, Others, Apoptosis
Bioactivity
VTP50469 fumarate is a highly selective and orally active inhibitor of Menin-MLL interaction (Ki: 104 pM), and has potently anti-leukemia activity.
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OC(/C=C/C(O)=O)=O.CC(C)N(C(C)C)C(C(C=C(C=C1)F)=C1OC2=CN=CN=C2N(C3)CC3(CC4)CCN4C[C@@H]5CC[C@H](CC5)NS(C)(=O)=O)=O.CC(C)N(C(C)C)C(C(C=C(C=C6)F)=C6OC7=CN=CN=C7N(C8)CC8(CC9)CCN9C[C@@H]%10CC[C@H](CC%10)NS(C)(=O)=O)=O.OC(/C=C/C(O)=O)=O.OC(/C=C/C(O)=O)=O
Molecular Formula
C76H106F2N12O20S2
Molecular Weight
1609.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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