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WAY-213613

Product Specifications

CAS Number

868359-05-1

Target

Transporter

Related Pathways

Metabolism

Bioactivity

WAY-213613 is a potent and selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 (IC50: 85 nM EAAT2), displaying 59- and 44-fold selectivity over EAAT1 and EAAT3 (IC50s: 5 and 3.8 μM, respectively) . WAY-213613 shows no activity at ionotropic and metabotropic glutamate receptors.

Smiles

N[C@@H](CC(=O)Nc1ccc(Oc2cc(F)c(F)cc2Br)cc1)C(O)=O

Molecular Formula

C16H13BrF2N2O4

Molecular Weight

415.19

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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