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WAY-213613 hydrochloride

Product Specifications

CAS Number

2450268-84-3

Target

Transporter

Related Pathways

Metabolism

Purity

0.9937

Bioactivity

WAY-213613 hydrochloride is a potent, selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 with IC 50 of 85 nM. WAY-213613 hydrochloride inhibits EAAT1 and EAAT3 with IC50 values of 5 and 3.8 microM, respectively. WAY-213613 hydrochloride shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function and can be used for the research of central nervous system [1] [2].

Smiles

N[C@@H](CC(Nc(cc1)ccc1Oc(cc(c(F)c1)F)c1Br)=O)C(O)=O

Molecular Formula

C16H13BrF2N2O4

Molecular Weight

415.19

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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