WAY-213613 hydrochloride
Product Specifications
CAS Number
2450268-84-3
Target
Transporter
Related Pathways
Metabolism
Purity
0.9937
Bioactivity
WAY-213613 hydrochloride is a potent, selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 with IC 50 of 85 nM. WAY-213613 hydrochloride inhibits EAAT1 and EAAT3 with IC50 values of 5 and 3.8 microM, respectively. WAY-213613 hydrochloride shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function and can be used for the research of central nervous system [1] [2].
Smiles
N[C@@H](CC(Nc(cc1)ccc1Oc(cc(c(F)c1)F)c1Br)=O)C(O)=O
Molecular Formula
C16H13BrF2N2O4
Molecular Weight
415.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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