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VU0650786

Product Specifications

CAS Number

1809085-30-0

Target

GluR

Related Pathways

Neuroscience

Purity

0.9909

Bioactivity

VU0650786 is a selective and potent CNS-penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM) (IC50: 392 nM), exhibiting antidepressant and anxiolytic activity in rodents.

Smiles

C[C@@H]1CN(C(=O)c2cc(COc3ccc(Cl)cn3)nn12)c1cccnc1F

Molecular Formula

C18H15ClFN5O2

Molecular Weight

387.8

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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