VU0650786
Product Specifications
CAS Number
1809085-30-0
Target
GluR
Related Pathways
Neuroscience
Purity
0.9909
Bioactivity
VU0650786 is a selective and potent CNS-penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM) (IC50: 392 nM), exhibiting antidepressant and anxiolytic activity in rodents.
Smiles
C[C@@H]1CN(C(=O)c2cc(COc3ccc(Cl)cn3)nn12)c1cccnc1F
Molecular Formula
C18H15ClFN5O2
Molecular Weight
387.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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